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Simparica Trio 44.1-88 lbs. Dogs
(100) reviews
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Simparica Trio 11.1-22 lbs. Dogs
(78) reviews
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NexGard Chewables for Dogs 24.1 to 60 lbs.
(624) reviews
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Simparica Trio 22.1-44 lbs. Dogs
(44) reviews

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NexGard Chewables for Dogs 60.1 to 121 lbs
(548) reviews
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NexGard Chewables for Dogs 10.1 to 24 lbs.
(572) reviews
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Simparica Trio 5.6-11 lbs. Dogs
(21) reviews
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Revolution Plus Topical Solution 11.1-22lbs Cat
(61) reviews

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Simparica Trio 88.1-132 lbs. Dogs
(24) reviews
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NexGard Chewables - Orange for Dogs 4 to 10 lbs.
(193) reviews
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Simparica Chewable for Dogs 44.1-88 lbs
(36) reviews
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Credelio Chewable Tablet for Dogs 50.1-100 lbs
(18) reviews
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Simparica Trio 2.8-5.5 lbs. Dogs
(6) reviews
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Simparica Chewable for Dogs 22.1-44 lbs
(22) reviews
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Revolution Topical Solution for Puppies and Kittens up to 5lbs
(16) reviews
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Simparica Chewable for Dogs 11.1-22 lbs
(39) reviews
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Credelio Chewable Tablets for Dogs 12.1-25 lbs
(17) reviews
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Credelio Chewable Tablet for Dogs 25.1-50 lbs
(19) reviews
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Revolution Plus Topical Solution 2.8-5.5lbs Cat
(5) reviews
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Simparica Chewable for Dogs 5.6-11 lbs
(13) reviews
Trifexis Chewable Tablets for Dogs 10.1 to 20 lbs
(129) reviews
$119.99
Trifexis Chewable Tablets for Dogs 20.1 to 40 lbs
(86) reviews
$122.99
Trifexis Chewable Tablets for Dogs 60.1 to 120 lbs
(106) reviews
$127.49
Advantage Multi Topical Solution for Cats 9.1 to 18 lbs
(49) reviews
$103.99
Trifexis Chewable Tablets for Dogs 40.1 to 60 lbs
(79) reviews
$125.49
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Credelio Chewable Tablet for Dogs 6.1-12 lbs
(8) reviews
Trifexis Chewable Tablets for Dogs 5 to 10 lbs
(42) reviews
$113.99
Advantage Multi Topical Solution for Dogs 55.1 to 88 lbs
(39) reviews
$115.99
Advantage Multi Topical Solution for Dogs 9.1 to 20 lbs
(46) reviews
$115.99
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Revolution Topical Solution for Cats 15.1-22 lbs
(46) reviews
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Simparica Chewable for Dogs 88.1-132 lbs
(7) reviews
Advantage Multi Topical Solution for Cats 5.1 to 9 lbs
(6) reviews
$103.99

Comfortis Chewables for Dogs 5 to 10 lbs. and Cats 4.1 to 6 lbs
(11) reviews
$106.07
Advantage Multi Topical Solution for Dogs 3 to 9 lbs
(21) reviews
$115.99
Advantage Multi Topical Solution for Dogs 20.1 to 55 lbs
(36) reviews
$115.99
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Revolution Topical Solution for Dogs 85-130 lbs
(21) reviews
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Credelio Chewable Tablet for Dogs 4.4-6 lbs
(3) reviews
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Simparica Chewable for Dogs 2.8-5.5 lbs
(1) reviews
Advantage Multi Topical Solution for Dogs 88.1 to 110 lbs
(16) reviews
$115.99
Advantage Multi Topical Solution for Cats 2 to 5 lbs
(2) reviews
$59.29

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Related Articles & Questions

Health & Wellbeing
How Long After Pest Control Is It Safe for Pets?
You may have heard that flea and tick prevention are crucial for dogs and cats, but do you know why? Petco is sharing why and how to prioritize pest prevention for your pet.
Updated on June 19th, 2026
Health & Wellbeing
Protect Your Pet: Flea & Tick Control Solutions for Dogs & Cats
Learn how to remove flea and ticks. Petco has flea and tick removal services for dogs and cats. Get fleas and ticks removed at your neighborhood Petco.
Updated on April 9th, 2026
Health & Wellbeing
Debunking Flea & Tick Myths: 5 Truths to Keep Your Pet Safe & Healthy
There's a lot of information out there regarding fleas and ticks—unfortunately, not all of it is accurate. Fleas and ticks can bring about a number of health issues in your pet.
Updated on October 23rd, 2025
Health & Wellbeing
Flea Infestation in Dogs & Cats: Symptoms, Treatment & Prevention
Read more about the different types of flea treatments and how they work to help eliminate fleas from your pet for their safety and happiness.
Updated on June 19th, 2026
Health & Wellbeing
Dog Fleas: Prevent, Treat & Eliminate Infestations – Ultimate Guide
Learn about fleas: their life cycle, how they spread, how to detect a flea infestation, and how to protect your dog and home.
Updated on October 23rd, 2025
Vet Q & A
What's cheap flea & tick control for feral cats I can't handle?
You may benefit from contacting the company directly and asking for coupons or free samples. You might consider giving your local SPCA or discount clinic a call as well. They may know more about discounted options in your area.
Updated on September 24th, 2025
Vet Q & A
Chewable vs topical flea/tick meds: Which is best and most affordable?
With oral prevention there are no issues with bathing/swimming interfering with the product's efficacy as well as they don't typically lose any effectiveness between doses compared to topical flea/tick medications. There are also more chances for errors in applying topical medications compared to oral medications. Topical medications also rely on the skin absorbing them appropriately which rarely doesn't happen. I can't comment on the cheapest effective brand as prices can vary among areas as well as certain products can be discounted as part of a promotion depending on a veterinary clinic, online pharmacy and store. However ineffective products in my experience include Hartz and most collars.
Updated on September 24th, 2025
Vet Q & A
What are the best flea preventives besides collars or shampoo?
Here is a selection of preventives: Spot-ons and/or chews: Advantage, Advantix Advantage Multi Frontline (ticks as well) Bravecto spot on (ticks as well) - for cats, in tablet form for dogs Simparica, Nexgard Revolution I hope you find something that suits you and your dog.
Updated on September 24th, 2025
Vet Q & A
What's the safest tick and flea treatment for my pug and my family?
Hi, thanks for using Petco Pet Education Center, formerly Petcoach! If you have access to the oral flea and tick preventatives (Nexgard, Simparica or Bravecto) they work the best. Or the Seresto Collar (lasts for 8 months). Otherwise I would use the spot on (advantixx, etc). I hope this helps!
Updated on September 24th, 2025
Vet Q & A
My dog needs flea/tick prevention. What's best without sweet smells?
I do not recommend any flea or tick shampoos, these are usually not safe products and not as long lasting as more modern preventive treatment for fleas and ticks. here is the list of the best flea products on the market. Spot ons: Revoulution Advantage Advantage Multi Frontline (ticks as well) Tablets: Trifexis/comfortis Bravecto (ticks as well) - for dogs Collar: Seresto ( (ticks as well) House spary: Indoorex
Updated on September 24th, 2025

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