Vet Q & AWhat are good Heartguard alternatives for my dog's heartworm?
Fortunately, there are a number of heartworm preventatives similar to Heartgard, including TriHeart Plus and Iverhart. Other options for heartworm prevention have different active ingredients and include Trifexis, Interceptor, Sentinel, Revolution, and Advantage Multi. Simba's vet will be able to prescribe another option and make sure that Simba has had a recent heartworm test.
Updated on September 24th, 2025