FRONTLINE Cat Products

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FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs.
(3636) reviews
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FRONTLINE Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs.
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FRONTLINE Plus Flea and Tick Treatment for Cats over 1.5 lbs.
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FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs.
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Related Articles & Questions

Health & Wellbeing
Protect Your Pet: Flea & Tick Control Solutions for Dogs & Cats
Learn how to remove flea and ticks. Petco has flea and tick removal services for dogs and cats. Get fleas and ticks removed at your neighborhood Petco.
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Ringworm in Cats: Identify, Treat & Prevent This Fungal Infection
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Vet Q & A
Cat's flea treatment not working. Can I safely apply Frontline now?
Since both Sentry and Frontline use the same active ingredient (fipronil) it is unlikely that you will see better protection switching to the Frontline. You will need to choose a product with a different ingredient, like Advantage or Revolution or a Seresto collar. If you choose to use another topical, I would recommend bathing your kitty today to remove any remnants of the Sentry, and wait 3 days to apply the next topical. It is important to wait after bathing so that the natural body oils have time to coat the skin to ensure adequate absorption. You do not need to wait or bathe to use a Seresto collar.
Updated on September 24th, 2025
Vet Q & A
Can I apply Frontline to my cat a week after Sergeant flea treatment?
Cats can be sensitive to flea medications. For that reason it is safest to wait 2 weeks between products even with different ingredients. Your vet can prescribe a cap star which is a pill that will last for a day that can help while you wait the remaining time
Updated on September 24th, 2025
Vet Q & A
My cat got Frontline spot-on, but I still see fleas. How long does it take to work?
Thanks for using Petco Pet Education Center, formerly Petcoach! Frontline is indeed effective. However, it may take a few days to see effect. Hopefully, it does work for Shadow. However, if no effect is observed, consider checking in with your veterinarian as other options could be attempted like Bravecto for example and even Capstar which has more of an immediate effect. Best of luck!
Updated on September 24th, 2025
Vet Q & A
Frontline for kittens: How long until fleas are gone and my home is safe?
Frontline will kill fleas within 24 hours and ticks within 48 hours. To be safe, you should also treat all your cats as well. A majority of a flea population lives off the pet, only hopping on to feed. A flea treatment and prevention program will include treatment of the pet and the environment. Use a preventative for at least 3 consecutive months, preferably year round.
Updated on September 24th, 2025
Vet Q & A
Cat still has fleas after Frontline. How long to wait for Advantage?
Wait at least one more week. Be sure to apply the liquid directly to the skin, not on the fur. If Cricket has been bathed, or will be bathed, wait at least 2-3 days before or after a bath. These topicals use the oils in the the skin to spread. A bath removes the oils which can affect the treatment. Use the appropriate size for her weight. Don't forget to treat the environment, since most fleas live off of the pet. Vacuum everywhere and dispose of the bag or empty the canister outdoors immediately after. Wash all bedding in the hottest water allowable by fabric and dry in the dryer. Use a cat safe area treatment to prevent reinfestation.
Updated on September 24th, 2025

FRONTLINE Cat Products

FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs.

FRONTLINE Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs.

FRONTLINE Plus Flea and Tick Treatment for Cats over 1.5 lbs.

FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs.

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